Japan joined the world in mourning after the Vatican proclaimed Pope Francis’ death on Easter Monday, commending the pontiff’s lifelong efforts in delivering the message of peace, which included a trip to Hiroshima and Nagasaki.

Prime Minister Shigeru Ishiba, in a statement issued Monday night, said he was extremely saddened to hear the news of the pope’s death.

“Since 2013, Pope Francis has dedicated himself to protecting the environment and promoting peaceful diplomacy with a strong voice supported by approximately 1.4 billion Catholics,” he said. “The demise of Pope Francis is not only a great loss for the people of Vatican and Catholics, but also for the international community.”

The prime minister and Foreign Minister Takeshi Iwaya also sent separate messages of condolence to the Vatican on Monday.

Japan's national flag was flown at half-staff in front of the Prime Minister's Office and other government buildings on Tuesday in mourning of the late pontiff, who is fondly remembered in the country for his historic 2019 visit to Hiroshima and Nagasaki where he met with atomic bomb survivors and called on the world to abolish nuclear weapons. He was the first pope to visit Japan in 38 years.

Toshiyuki Mimaki, the co-chair of Nobel Peace Prize laureate Nihon Hidankyo, a Japanese organization composed of atomic bombing survivors, said the pope’s death was “truly saddening.”

“Politicians stick to their respective ideologies and principles, which can lead to war, but the pope was different. He came across as a kind and compassionate person,” he said.

The Catholic community in Japan also mourned the loss of its leader.

In a letter addressed to members of the Catholic Church in Japan, Archbishop of Tokyo Tarcisio Isao Kikuchi, who was made a cardinal by the late pope in December, offered his prayers and expressed his appreciation for the pope’s lifelong service.

“For the Church in Japan, it was a vivid and tangible experience of our shepherd's presence. We were spiritually set aflame by directly hearing his voice,” the cardinal wrote of the late pope’s Japan visit in 2019. “We have lost a powerful shepherd filled with love and compassion.”

The sister of Iwao Hakamata, a Catholic former death row inmate who was found not guilty and fully exonerated of a 1966 murder case last year, offered condolences during an interview, according to Jiji Press. Hideko Hakamata attended the papal Mass at the Tokyo Dome in 2019 in place of her brother, who could not attend due to illness, on Francis' invitation. They also received a letter and rosary from the late pope in January following the ex-boxer's exoneration.

With Francis' death, the Holy See is now vacant. The Catholic Church in Japan has two cardinals eligible to vote for a new pope — Kikuchi and Archbishop of Osaka-Takamatsu Thomas Aquinas Manyo Maeda, who Francis made a cardinal in 2018.

It will be only the second time in history that two Japanese cardinals join the conclave at the Sistine Chapel to elect a pope; in 2005, then-Cardinals Stephen Fumio Hamao and Peter Seiichi Shirayanagi voted in the conclave that elected Benedict XVI as the new pontiff following the death of Pope John Paul II.